Lactobacillus paracasei

Lactobacillus paracasei 8700:2

8700:2 (Probi)

Lowering the risk of upper respiratory infections during periods of physical stress, often combined with strain HEAL9.

Moderate Evidence12+ indexed studies

Quick Overview

At a Glance

Researched Benefits

  • Clinically studied to reduce the duration and frequency of the common cold
  • Supports a balanced immune system without overstimulating it
  • May help lower triglycerides and support metabolic health alongside immune benefits
  • Well-tolerated with an excellent safety track record in human trials

Usage & Application

Clinically Studied Dosage

1–2 Billion CFU/day (often as part of a dual-strain formula with L. paracasei HEAL9)

Available Forms

CapsulesPowder sachetsChewable tabletsFunctional beverages

Clinical Evidence

Respiratory Infection Defense for Active Lifestyles: Lactobacillus paracasei 8700:2

Lactobacillus paracasei 8700:2 is a well-characterized probiotic strain originally isolated in Sweden and developed by Probi AB. Like all Lactobacillus paracasei strains, it is a Gram-positive, rod-shaped bacterium that naturally thrives in fermented foods and the human gut. Think of it as a friendly security guard that sets up camp in your digestive system — and from there, sends out signals that keep your whole immune defense system sharp and ready. What makes 8700:2 special is that it is almost always studied and used alongside another Probi strain called HEAL9. Together, these two strains form a dynamic duo that targets the gut-immune axis, meaning they train your gut's immune cells to be better prepared when real threats — like cold viruses — come knocking. Research has also confirmed that accurate strain identification and counting methods (including advanced DNA-based testing) have been validated specifically for this strain, ensuring that what's on the label is actually what's in the bottle.

The headline benefit of L. paracasei 8700:2 is its potential to reduce the number of days you spend feeling miserable with a cold. In clinical studies, people who took the 8700:2 + HEAL9 combination reported getting fewer colds during the winter months and, when they did get sick, recovering significantly faster than those taking a placebo. The immune-supporting effect seems to work behind the scenes: the bacteria interact with immune cells in the gut lining, nudging the body to maintain a more balanced and responsive defense system — not overactive (which leads to inflammation), but alert enough to clear infections quickly. Beyond the common cold, this strain has also attracted attention for its cardiometabolic benefits. Research suggests it may help lower triglyceride levels, slow weight gain, and support healthy blood sugar balance — making it potentially useful for people dealing with metabolic syndrome or those simply trying to maintain a healthy weight. Some evidence also points to L. paracasei 8700:2 supporting gut barrier integrity, which means it may help keep the gut lining tight and prevent unwanted substances from leaking into the bloodstream — a concept sometimes called 'leaky gut.'

L. paracasei 8700:2 has a strong safety record and is considered well-tolerated by healthy adults. It has been studied in randomized, double-blind, placebo-controlled trials — the gold standard of clinical research — with no serious adverse effects reported. It is most commonly found in capsule or powder-sachet form and is typically taken once daily, often as part of a dual-strain formula. Because probiotic health benefits are strain-specific and dose-dependent, it's worth looking for products that list both strains (8700:2 and HEAL9) on the label. This combo is particularly popular among athletes, frequent travelers, parents of young children, and anyone who finds themselves catching one cold after another. As with any supplement, people who are immunocompromised, pregnant, or managing a serious health condition should check with their doctor before starting. In addition to immune support, secondary benefits include mild cholesterol and triglyceride management, gut microbiota balance, and potential support for stress resilience via the gut-brain axis — making this strain a solid all-rounder for everyday wellness.


Common Questions

Frequently Asked Questions


Sources

Scientific References

Curated By

Clara Hayes

Clara Hayes

Lead Research Editor

Clara leads the curation and verification of microbiome research for our platform. With extensive experience in translating complex scientific literature into accessible insights, she ensures every strain profile is grounded in peer-reviewed evidence and contextual accuracy.

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Medical Disclaimer

The information provided on probioticstrains.com is intended for educational and informational purposes only. It does not constitute medical advice, diagnosis, or treatment. Strain profiles and clinical summaries are compiled from published peer-reviewed literature. While we may evaluate or highlight specific commercial formulations, our insights are always grounded in available scientific evidence. Always consult a qualified healthcare provider before starting, changing, or stopping any supplement or health regimen.