Bifidobacterium lactis

Bifidobacterium lactis DN-173 010

DN-173 010 (Bifidus Regularis / Activia)

Speeding up gut transit time and easing occasional constipation and bloating.

Strong Evidence12+ indexed studies

Quick Overview

At a Glance

Researched Benefits

  • Clinically shown to increase bathroom regularity in as little as one week — without harsh laxatives or side effects.
  • Helps soften stools and reduce straining, making trips to the bathroom far more comfortable.
  • Backed by multiple large-scale human trials across different countries, ethnicities, and age groups — among the most studied probiotic strains for constipation.
  • Also supports overall digestive comfort and bloating relief, even in people without diagnosed gut conditions.

Usage & Application

Clinically Studied Dosage

10–12.5 Billion CFU/day (1 serving of a fortified fermented dairy product)

Available Forms

Fermented dairy drinks (yogurt-style)CapsulesTabletsPowder sachets

Clinical Evidence

Faster Gut Transit and Relief from Occasional Constipation: Bifidobacterium lactis DN-173 010

Bifidobacterium lactis DN-173 010 is a specific, patented probiotic strain belonging to the Bifidobacterium family — a group of friendly bacteria that naturally live in your large intestine and help keep your gut running smoothly. What makes this particular strain special is its remarkable toughness: it survives the harsh journey through your stomach acid and actually arrives in your intestines alive and active, ready to get to work. Think of it as a particularly resilient courier that actually delivers its package, while weaker bacteria get destroyed along the way. Once it reaches your colon, it gets busy influencing something called 'gut motility' — basically, how fast your intestines push things along. Researchers believe it does this by interacting with the gut's own nerve network and by producing short-chain fatty acids that stimulate intestinal movement, much like giving your gut a gentle, natural nudge.

The biggest claim to fame for this strain is its impressive ability to help with constipation and sluggish digestion — and there's real science behind that claim. People who struggle with going to the bathroom regularly, dealing with hard stools, or feeling uncomfortably bloated for days have seen meaningful improvements in clinical studies after just one to two weeks of daily use. Stool frequency goes up, the effort required to go decreases, and the consistency of stools becomes more comfortable — without causing urgency or loose stools. Beyond constipation, this strain has also shown real promise for people with Irritable Bowel Syndrome (IBS), particularly those whose IBS tends toward the constipation side. Users in these studies reported less bloating, improved gut comfort, and better overall quality of life. Even people without diagnosed digestive issues — just those who feel 'off' in their gut or regularly uncomfortable after meals — reported dramatically better digestive well-being after incorporating this strain into their daily routine. In one large study, over 80% of participants reported an improvement in digestive comfort after two weeks of daily consumption.

From a safety standpoint, Bifidobacterium lactis DN-173 010 has an excellent record. It has been tested across different age groups — from healthy young adults to elderly individuals — across multiple countries and ethnicities, and consistently shown to be well-tolerated with no significant side effects. Blood work, kidney function, and liver markers all remain normal during use, which is a reassuring sign for long-term safety. This strain is generally suitable for healthy adults, older adults (who are particularly prone to constipation), and women (who statistically experience constipation more often than men). It's most commonly found in fermented dairy products like yogurt drinks, but also appears in capsule and tablet supplement forms if you're dairy-free. For best results, daily and consistent use over at least one to two weeks is key — think of it less like a quick fix and more like a daily investment in your gut health. As a bonus, some research also suggests this strain may support lactose digestion and a healthier balance of gut microbiota more broadly, making it a versatile choice for general digestive wellness.


Common Questions

Frequently Asked Questions


Sources

Scientific References

Curated By

Clara Hayes

Clara Hayes

Lead Research Editor

Clara leads the curation and verification of microbiome research for our platform. With extensive experience in translating complex scientific literature into accessible insights, she ensures every strain profile is grounded in peer-reviewed evidence and contextual accuracy.

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Medical Disclaimer

The information provided on probioticstrains.com is intended for educational and informational purposes only. It does not constitute medical advice, diagnosis, or treatment. Strain profiles and clinical summaries are compiled from published peer-reviewed literature. While we may evaluate or highlight specific commercial formulations, our insights are always grounded in available scientific evidence. Always consult a qualified healthcare provider before starting, changing, or stopping any supplement or health regimen.